Before equal temperament, definitely. This is based on a theorist from 1713: https://ledgernote.com/blog/interest...tics-emotions/

After equal temperament, its up for debate. Some swear they feel the difference, others swear those people are experiencing a placebo effect or something, and others swear you should tune to 432hz to be in tune with the universe and that 440hz tuning is part of a conspiracy. It gets pretty murky lol.