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Old 26th June 2020
  #6
Gear Head
 

OP

I was having issues with low latency as well until I started playing around with processor affinity settings. FOR ME, in Pro Tools with a MOTU 1248, I can run multiple soft synths (Omni, Kontakt, Massive, etc) and light processing at 64 sample buffer latency (no pops or clicks for 3 hours) - BUT only if I adjust the Processor Affinity to FFE on my 8700K system. I do not know why (thread contention on one of the cores ?), but on my current and past systems this has been required in PT. I always run at 24/96. If things get real heavy, I might drop to 128 samples, but that's almost equivalent to 256 samples at 48KHz.

Here is more info from an older thread I submitted at the duc: http://duc.avid.com/showthread.php?t=383052

YMMV. Hope this helps.