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Old 4th March 2016
Deleted User
+1 to what Monotremata said as well.

Midi out is sending your main control info and SYSEX data from the synths for patch backup and all that, the thrus are just a copy of that info. Most midi boxes that say out on them are in fact THRU ports. Like my midi patchbay. My controller is on one port and the other OUTS are going to my synths so they are really a THRU port

I use a MOTU MTPAV USB here, no issues, 8 in and 8 out. I have a 2nd one networked to it for 16x16