Yes it can be a different transition. The typical problem that I encountered was that I expected the plug ins to sound and react like a piece of hardware. I began just closing my eyes and just tweaking on the controls to find a sound I liked. Once satisfied I would look at the settings and I began to accumulate a base of knowledge on that piece of software.
For vocals I have had good success with any of the following plug ins .
Sony Oxford EQ
TC Master X
I find that with the eq , the curve looks more extreme than a hardware piece and the converse is true for the compressors, definitely less is more. Sometimes it helps to have a number of each. Just experiment and find out what sounds good to your ear.