I love my RME AES HDSPe card for my main rig. You can use it with a laptop if you get an enclosure from Sonnet or OWC to house the PCIe cards and connect to your laptop (or desktop) with Thunderbolt 3 (or Thunderbolt 2 if you still prefer).
In my main studio I use nearly all the I/O channels of the RME AES HDSPe because I:
1) Send the unmastered source to two different DAC units so I can choose on my mastering console which one feeds the analog gear for a particular song/project.
2) Send the end of my analog chain back to my DAW feeding two different ADC converters and in the DAW I can toggle between the two to choose a favorite.
3) Send the main output of my DAW to my monitor controller via AES.
4) Send a fully unprocessed version (no plugins, no analog gear) to my monitor controller (via AES) so I can instantly toggle between my processing and the totally raw version.
5) Send a digital copy of whatever I'm listening to on my monitor controller to in to the RME AES card so that I can use a great metering app (Flux Pure Analyzer) to monitor whatever I'm listening to be it my DAW, iTunes, TIDAL, vinyl, MacOS etc.)
6) Send a digital copy of what I'm listening to OUT to my hardware Dorrough meters to monitor the loudness of whatever I'm listening to.
7) I also send a copy of the unmastered audio to another hardware Dorrough so I can monitor the level both pre and post analog chain.
So, if you want to get fancy with it all, the RME AES card (or Lynx AES16e if you want to save a little money but have a few more headaches) can be a really great tool for advanced routing.
If you want to just keep it simple like I do at my home setup, I've found the MUTEC USB to AES interfaces to be the most stable. I tried the MOTU 8D (very unstable) and Dante Virtual Soundcard (never got it working) and the MUTEC is by far the most stable and easiest to work with.
MC-3+ USB:
MUTEC - Professional A/V and High-End Equipment - MC-3+ USB
Or the discontinued MC 1.2 can still be found on eBay and others:
MUTEC - Professional A/V and High-End Equipment - MC-1.2
I'm told they will eventually refresh the 1.2 but did not give a timeline.