Agreed that it would be amazing to clone the Xpander. I have one, and it's an amazing synth that does stuff that few others can. What it doesn't do well, however, is 'bread and butter' synth sounds. Something like a Prophet 600 gligli is much better for that, and the reason is in the chips.
Xpander used later stage Curtis chips that didn't sound as good, the oscillators in the 3374 have this annoying mid-rangey sonic coating that is difficult to eq away (which gets in the way of the basic tone of the chroma polaris or the akai vco synths). With a lot of resonance you don't hear it as much (ie: Polaris), and with the non-standard filter types of the Xpander, it ceases to matter. But taken on its own, the 3374 ain't a great oscillator tone. The 3340, the reissues vco chip, is beyond classic (Prophet 600, Obxa, etc.). If you're gonna do an Xpander reissue that in any way 'improves' upon the original, use that chip instead! Xpander has many strong points, but its raw oscillator tone is simply not one of them, 3340 all the way.
Also worth saying that the 'filter trick' that Tom Oberheim used to get a standard Curtis chip to give him 15 filter types is mostly done with the wiring AROUND the chip. Any old Curtis chip filter will do if the wiring around it is right. Each Curtis has its own sound, but the 3372 is the same curtis filter used in the Prophet 600 (I think, online account seem to vary!), and that's def one of the better ones. Point is, in terms of chips, he's already there.
As for interface, the interface on Xpander is amazing for what it could with the technology, but it's still not what I'd call immediate. So many easy ways that a modern DSP could improve upon that aspect without hurting the sonics at all.
The modular side of it is a major attraction to some, but semi useless to others. I'm more a traditional player kinda guy, so I've never used the CV options, but I can see where the modular folks would love it, and agreed, there's no reason why couldn't have a patchbay that goes way beyond CV. The ideal thing to do would be reissue the Xpander without CV, but then have a breakout unit (Xpander Expander?!) that has tons of CV for the modular crowd. Midi CC is great, but not if you're into modular.