With all due respect.... someone has to say it! As guitar player, I consider the Line6 products to be toys.
I would think VariAxe when I think "gift for little cousin Johnny", so he can play through headphones and not bother his parents.
dfegad Line 666, "digital modelling" vdrums, etc.
I recorded an "all digital" act once... v drums, guitar and bass pods, modeling synths, voicemodeling...
They sounded like complete ass, especially live, and have since gone back to "real" instruments. (they still suck)
Analog/Real gear has SO much more dynamic range than modelled crap, you can achieve much more powerful sounds that don't disappear in the mix.
Granted, I think vdrums and pods a great tools, especially for laying down scratch tracks/and or jingles, but I wouldn't be caught dead using them on a rock record, unless the artist's sound was specifically built around them. (think Omar Hakim's solo album - all vdrums).
For more experimental/electronic music, these tools have more uses, but for rock n roll? Nah, not for me.