Neither patch cables nor ground loops will cause a hiss, assuming that you're employing the correct terminology. You said it sounds like white noise - that's hiss.
Patch cables, ground loops, and badly shielded guitars will cause hums and buzzes but not a hiss. Hiss is nearly always caused by thermal noise, often exacerbated by excessive gain. It's either a bad tube, a defective resistor which is unlikely in a relatively new amp (or bad solder joint causing a resistance where there shouldn't be one), or simply the result of having the gain cranked too high which is amplifying the natural hiss of the amp (in which case all you can do is turn the gain down.)
Or you can check in the bottom of the amp's case and make sure you don't have a big snake hanging out in there.....
The Fender site says it's a high gain amp. High gain amps hiss when you turn them up. The only way to minimize (not eliminate) that hiss is to use a premium low noise tube in the front end of the high gain channel.