Sounds like ground loop hum. Single coils magnify the problem while humbucklers do not get rid of the problem they just cover it up.
I change my board quite a bit and I work to have a totally quite system with no noise on my single coils.
You need to power effects from an isloated port brick, do not daisy chain.
Electrical rule is you can give something higher mA than it needs (to an extent) but NOT less. A lot of guys use those daisy chained power supplies which in some low tech cases might work but end up causing more problems than they solve. Most younger players have little concern for their power supply rigging. I saw one guy on the internet who was using as std 9v 100mA wart to daisy an entire chain. That will work if the sum total of all the pedals is <100mA but it is a bad idea. (Sum total of all the pedals mA currents should be well less than the max rated output of the common supply.) Most quality power bricks have plenty of mA supply. Are you getting any bad pops from any true by-pass pedals?
That is a sure sign of ground problems. Fulltone used to do this to me all the time with bad popping due to by-pass pedals building a charge on the switch. I remove all the batteries from my pedals and everything gets fed from a BBE Supra-Charger that gets its power from a Furman power conditioner filter. Never underestimate the importance of your power feeds.
Getting rid of the batteries solves a lot of ground loop and charging problems. Some complain "what if the power goes out the batteries are like a backup". Seriously if the power goes out so does my amp, so sound is down. Besides I bloody hate batteries. Effects will almost always sound better and work to their full design w a good fixed and regulated power supply. Another problem with board noise is from the design of certain pedals which cause the tubes to become more sensitive to interference
(12AX7s are really sensitive to 60 cycle hum and radio) you get radio coming through or the 60 hz cycle hum of the electrical supply magnified by a nearby florescent fixture, when you are not playing.
Been my experience the Vox/JS Satchurator causes this a lot, probably are a lot of others. The solve for this type of interference or hum can be fixed by a Faraday cage, a copper grounded and insulated screen that goes over the V1 tube (see tubestore.com/tube cage like $17). Sometimes really major shielding and grounding on some guitars will kill it but not usually. The importance of a isolated, filitered and surge protected power supply is essential for a good pedal board and to suppy the amp with a constant, clean and regulated voltage.
Some companies will argue the very power cord to your amp will effect the sound of the amp. Do not cheap out anymore than you would use cheap line cables.
A Power Clamp (locks voltage at a constant 100v) Conditioner also helps to filter out noise in the electrical supply. Furman and Carvin made very reasonably priced main 110v supplies, Voodoo Lab and BBE made really good isolated bricks for pedals.
Remember, be sure to match the box's voltage and mA draw. You can give a pedal more mA than it needs but not less. Most pedals draw less than a 100 mA which is the usual port current on bricks. Good ones offer switches and some ports with uo to 200 mA and higher voltage for some rare effects. Never give a box more voltage than it is rated, you will fry it. Some like Fulltones can take a range
of 9-18v. Most are just 9v. I had a Morely Wah last year that was a 300mA draw, no brick could supply it so I ran a separate wart for it from a multi-suuply also fed by the Furman. My Whammy is a 200mA pedal and has a special high current wart.
If you're like me any sort of hum or interference is intollerable on my board. I work to get rid of it and to keep the sound HD.