The Euphonix System 5 and MC were controlling Nuendo and other DAW´s, to a more or lesser degree, before AVID bought the company.
At that time, DAW´s like Nuendo for instance didn´t have a dedicated long form controller made specifically for it, if you exclude the IK, which was a third party manufactured device.
But some form of basic controlling has been made available from various console manufacturers, using protocols such as OASIS, Eucon, HUI etc. Brands like AMS-Neve, SSL, Audient etc. Not to mention Smart AV´s Tango, which is basically a touchscreen controller with faders and an excelent and versatile controller.
Apparently we´re seing an interest again in specific controllers, Yamaha´s Nuage for Nuendo is an example, you got the Fairlight EVO and Quantum for some time now and apparently a new controller, Iris, made for Pyramix by Smart AV will be introduced at IBC next week.
When I said that it may be game over for certain AVID´s controllers, I was only expressing my opinion about the OP own expression towards other manufacturers´controllers.
Even if AVID may be targeting other DAW´s than PT as possible clients for the controller, which is good if they do, as competion is healthy, I think that in the first stages it will be specifically and primary intended to PT. Starting with the hardware interface.
But well, let´s wait and see. After all, IBC is in a few days time.