Soundminer is really speeding up my SFX editing. It's taking some time to get all of my effects ripped and cataloged but once they are in there, it's great. I'm using V4 Pro. Love the search functionality, ability to pitch right there in the app, spot to pro Tools, and even apply VST plugins. It's highly customizable as well. Only things is, it's not super cheap. But, if cutting FX is what you do, the price is easily justified.
Other programs may be great as well. This is the first one I've used. Before that I had my own rudimentary system for searching and organizing FX.