I'll take a stab at it, if for no other reason than it may attract someone who knows what they are doing to save you from me.
Not sure about all three drives, but there is software like Paragon that let's you make an iso copy of your drive that you can reload if you go FUBAR.
Also don't know about Cubase, but Sonar will let me tell it to auto-save every X seconds/minutes, and where to save to. So, if I had any sense, I could send the auto save to the backup drive. Hm, maybe I oughta think about that...
Hope that helps, man.