Someone asked: "I'm not sure, but will it run as full 64-bit DAW on Vista-64 ? Hopefully it does, and also run as a 64-bit DAW on the next Mac OSX Snow Leopard."
(Note: I'm PreSonus's marketing communications manager. I hope I don't wear rose-colored glasses, but I don't want to mislead anyone about where I'm coming from. ) Studio One
employs a 32-/64-bit floating point, mixed-mode engine. This means that the audio engine can automatically switch between using 32-bit, single-precision floating-point and 64-bit, double-precision floating-point math, on the fly, depending on the capability of the plug-ins (VST/AU effects, etc.) inserted into the signal chain. The software engine operates in 64-bit even if the OS is not 64-bit. The reason it can switch to 32 bit is to accommodate lower-resolution VST and AU plugs and such. The proprietary native effects that are bundled with Studio One
are 64-bit, so you can have a 64-bit end-to-end signal path if you just use the native plugs. Which, in my admittedly biased opinion are very, very good, and you get all the basic food groups (dynamics processors, EQs, reverbs, delays, chorus, flanger, phaser, etc.).
The driver programmers are still finishing the 64-bit Vista drivers for PreSonus interface hardware but that just affects using the interfaces with Vista 64. Besides, Studio One
supports any ASIO, Core Audio (Mac OS X), Direct Sound (Windows XP), and Windows Audio Session API (Windows Vista) interfaces, not just PreSonus interfaces. However, it will have templates that automatically configure it for PreSonus hardware, which is very nifty.