2 soundcards in 1 PC

[azwun25]

shouldn't be a problem. some hardware doesn't like to see other hardware connected..like the digi stuff..you can't use them at the same time but they can both be connected

[JimmySX]

Still the best thing to do is to have 2 smililar cards to avoid driverissues (asio).

[lukasxpop]

I've used multiple cards without issues.

using simultaneously - but with differnt programs.

actually i usually have a second soundcard cheap for "System Default" for media player etc..

[CorkyTart]

So lets say for example, you can have Nuendo running using the MOTU HD 192s with the PCI 424 card, go through a summing box and then go into Cubase using a (Insert very high end converter and soundcard here) all on the same computer at the same time?