Originally Posted by RiF
And guitar software (see your quote below).
For reamping I agree that a cleanest signal possible could be what to reach for.
I still find it a little unnecessary to use mic pre-amp to convert a hi-z signal into a line signal:
Hi-z > DI > Mic pre-amp > line out > interface
When all that's needed really is:
Hi-z > Line-amp > line out > interface
But you're right, a Mic pre with a nice transformer HI-z input - or a Tube DI like the one from A-Designs might bring something nice to a digital amp sim.
But I would be carefully not to drive the signal too hot as tube and transformer distortion might affect some software hi-gain in a bad way.