Which kind of shuffle are we talking about?
I can't think of a form of shuffle which would make it worth compromising musical integrity.
If you're on iPod/Pad/Tunes shuffle, turn on soundcheck.
If you're talking about a multiple CD stacker in a car, just adjust the volume as you have the volume at arm's reach (or even on the steering wheel maybe)
Considering CD apparently on its last legs (commercially anyway), I think the justifiable need to 'compete' for level is a fast becoming a pointless plight of years gone by.
As Thor said, surely we should be focussing on the aesthetic of the sound and put quality first.