I've had my current '11 MBP for about a year now. It certainly is a desktop / Mac Pro replacement for me. No problems what so ever and it's pretty much on all the time, or sleeping at night. I rarely ever shut it down and use it for live performance. I replaced the stock HD with a 7200rpm as well as the RAM to 8gb.
Analog synth or plugin? The elitists go silent when a blind test is involved.