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After starting this thread nearly a year and a half ago, running a PCI RME AES-32 interface, 2 PCIe UAD-2 cards, USB mouse and keyboard, MIDI communication with an external synth via USB, 2 USB external drives, a Tranzport connection via USB, and using Reaper as my DAW, I've had zero issues...not even a hint at one.
At least for me, fortunately, my initial concern about PCI assignments turned out to be no issue at all. W7 on my i7 920 has been rock solid and quite an improvement over all the tweaks and fixes required to get XP up to snuff. Nice to concern myself with making music and not wondering what the heck is going on with DAW.
Regards,
DB
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