I have used Samplitude since version "2496" and have to agree with much of what has been said here. I have also tried other DAWs and found that their workflow was simply not as intuitive. For those who have said that the newer versions don't sound as good as the older ones, I'll share my experience: When I got a new comp, I installed Sam10 but I also kept my old one with Sequoia7 just in case. Both sound fantastic. I am using the new Sam 10 "quad core" engine on a quad core comp and it sounds as good as Sequoia did on a single core. Maybe that's the key, IDK. As for sounding better than others, here are some opinions:
Samplitude, Sequoia Kahne Samplitude, Sequoia Hoskulds
The bottom line for me is that while I have heard that Sam/Sequoia sounds better than other DAWs, I have never heard anyone say that
anything else sounded better than Sam/Sequoia! Form your own opinion with your own ears, but be sure to use good monitors in doing so!
Quad Core AMD 2.3GB Phenom processors
4GB DDR2 memory
6 7200rpm Fluid bearing hard drives in RAID 1&5 +1 archive HD
Emu 1820m interface (w/ AKM AK5394a A/D processors)
Samplitude 10 pro & Sequoia 7
total over 800 DSPs incl Waves & UAD
Emu Proteus VX
30GB Proteus/Emulator Samples
26" LCD monitor
15"Tannoy Gold dual-concentric (Westminister) reference monitor drivers