One more point - I upgraded to Sequoia from Samplitude on v9 and am now on v10.2.1.
The other day I had to install it on a new laptop that runs under Vista - problems (of course).
A quick phone call to tech. support in the USA (perfect for people ringing from the UK in the evening) and everything was sorted very quickly by an extremely nice chap on the phone there.
I find Samplitude support (not that you need it very often) is absolutely superb and the on-line forum is extremely helpful with developers looking in and answering where necessary.
A No.1 recommendation from me.