My ITB mixing got considerably faster when I started to make templates with my 'go to' plugs and mixer setup. These can always be replaced if they don't work.
On a board everything is already layed out for you, eq's, comps (if your lucky!), auxes, etc. whereas the DAW is a blank panel, so having these setup is a huge time saver!
My biggest time and flow killer when mixing ITB for me is being forced to bounce things because of running out of horsepower.