I used to use a Mackie Control to control Cubase SX, which was a good controller for what it was. However I wanted more faders and ended up buying a Tascam DM-24 digital mixer and mix digitally out of the box. It has made it easier for me to mix. I'm still waiting for the firewire card to come out for it.
Using the Mackie Control sometimes would push the software faders more or less than I wanted. Using the DM24 the summing is done on that board so what you see is what you get.