I'm using a mackie control myself. If i could operate a mouse by touch without looking at the screen, i would.
Once the session is set up, an entire tracking session can be done without touching the mouse, if desired.
Using a mouse to manipulate transport controls was kind of odd. Keyboard control works too, but that wasn't the question.
I dislike mice, but i hate trackballs. Trackballs are for centipede and marble madness. And if you drink at bars, for playing golf.
Edit: I did take the time to really learn the Control, btw. Even adding plugs on the inserts isn't so bad. No more difficult than a LARC, only with more "patches." If you don't put any effort into learning something new, it will be slow. The control surface is actually easier to "get" than an MC505.
Editing is all about the mouse and keyboard though. But editing is not tracking, not overdubbing, and not mixing. That is just my workflow though; i know plenty of you edit while tracking and mixing.