I think you might well be right that it gets you an extra 10% of clarity and definition but I'm not willing to endanger the more important 90% of my mix because I have to devote so much time and braincells to this issue and agonizing way of mixing. If I somehow came to be convinced this was the only way left for me to improve my mixes, you can be assured I would start to mix exclusively on a mixing board and out of PT. I have so much stuff left yet to better in my mixes I'm covered for at least one or two lifetimes!
I'm not dismissing your point though, but for me it's not worth the stress to fret over.